The hard facts – Comparing the biggest beauty trends of 2026
At our luxury skin clinic on Richmond Hill, we are often asked the same question by discerning clients:
“With so many advanced anti-ageing treatments available, which one truly delivers the best long-term results?”
The aesthetic industry has seen a surge of innovation in 2026, but not all treatments are created equal. This in-depth guide is designed to help you understand the key differences, benefits and clinical credibility behind the most talked-about facial treatments of the year – so you can make an informed, confident investment in your skin.
Following on from last week’s educational blog, we’ve created a clear and simple comparison between:
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ASCE Rose Stem Cell Exosomes (combined with Sylfirm X RF Microneedling)
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Polynucleotides (Salmon DNA / “Salmon Sperm”)
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Profhilo
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PRP (Platelet Rich Plasma / Vampire Facial)
All clinical information is accurate and up to date as of July 2025.
| Rose Stem Cell Exosomes with RF Microneedling | Salmon Sperm / Polynucleotides | Profhilo | PRP | |
|---|---|---|---|---|
| Method of delivery | Non-injectable | Injectable | Injectable | Injectable |
| Treatment areas | Suitable for full-body application | Face, neck, eyes décolletage, hands | Face and neck (not suitable for forehead or eye area) | Face, neck, eyes décolletage, hands |
| Result consistency | Highly consistent due to controlled purification, laboratory processing and source standardisation | Variable | Variable | Variable; dependant on individual blood quality |
| Clinical evidence | Over 2.2 million treatments worldwide across 70+ countries | Approximately 90 clinical studies (variable quality) | Limited published clinical data | Limited published clinical data |
| Recommended sessions | 1-6 sessions depending on skin concern severity | Typically 2-3 sessions | Minimum of 2-3 sessions | Typically 3 sessions |
| Approximate cost per session | £800 (face, neck & eye area) | £2,000 – £3,000 (face, neck & eye area) | £500 | £550 |
| Downtime / side effects | Mild, temporary erythema associated with RF microneedling | Swelling, bruising, erythema; potential allergy risk for individuals with fish sensitivity | Redness, swelling, mild bruising and tenderness | Redness, swelling, mild bruising and tenderness |
| Contains growth factors | Yes | Yes | No | Yes |
| Contains peptides | Yes | Yes | No | Yes |
| Contains amino acids | Yes | Yes | No | Yes |
| Contains vitamins and minerals | Yes | Unclear | No | No |
| DNA free? | Yes | No | Yes | No |
| Improves collagen production | Up to 690% | Up to 47% | No clinical data | Average 46% – 89% |
| Improves elastin production | Up to 300% | No clinical data | No clinical data | No clinical data |
| Reduces hyperpigmentation | Up to 75% | No clinical data | No | Average 47.86% |
The Clinical Perspective – What Sets Each Treatment Apart?
When you strip away trends and marketing noise, the true value of a skin treatment lies in clinical evidence, formulation quality, consistency of results and long-term skin health benefits.
Once the facts are laid out side by side, the distinction becomes clear.
From a professional standpoint, ASCE Rose Stem Cell Exosomes represent the most advanced regenerative skin technology currently available in aesthetic medicine.
Here’s why we confidently lead with this treatment in our clinic:
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Backed by the highest number of clinical trials
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Pharmaceutical-grade purity and consistency
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Completely DNA-free, ensuring safety and biocompatibility
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Rich in growth factors, peptides, amino acids, vitamins, minerals and hyaluronic acid
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Proven to stimulate collagen production by up to 690%
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Non-injectable, making it suitable for clients who prefer advanced results without needles
When paired with Sylfirm X RF Microneedling, exosomes are delivered precisely where your skin needs them most – enhancing cellular communication, accelerating repair and dramatically improving skin quality, texture and firmness.
This is not a quick fix. This is true skin regeneration.
Can ASCE Exosomes Be Combined With Injectables?
Yes – absolutely.
If you currently enjoy injectable treatments such as Profhilo, polynucleotides or dermal fillers, ASCE Rose Stem Cell Exosomes can safely complement your existing regimen.
We simply ask that you always inform us of previous treatments so we can expertly plan the correct intervals and ensure optimal results.
Even for clients who love injectables, it’s important to understand this:
There is currently no injectable on the market that can replicate what ASCE Rose Stem Cell Exosomes achieve at a cellular level.
This is skin health in its purest, most advanced form – delivering results that are visible, long-lasting and foundational.
Investing in Your Skin – Not Chasing Trends
Choosing the right anti-ageing treatment is about far more than what’s trending on social media. It’s about:
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Your long-term skin health
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The quality of the formulations used
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Clinical evidence
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Expert assessment and bespoke planning
At our expert-led skin clinic in Richmond Upon Thames we specialise in working with clients who value excellence, results and integrity – and who are ready to invest properly in their skin.
We hope this guide has helped clarify the leading anti-ageing facial treatments of 2026 and given you confidence in choosing the approach that aligns with your goals.
As always, we’re here to guide you – warmly, honestly and expertly – every step of your skin journey.
